conformational change
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Conformational change — See also: Database of Molecular Motions A macromolecule is usually flexible and dynamic. It can change its shape in response to changes in its environment or other factors; each possible shape is called a conformation, and a transition between… … Wikipedia
Serpin — Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The name serpin is derived from this activity serine protease inhibitors. [cite journal |author=R. Carrell and J.… … Wikipedia
Antithrombin — Serpin peptidase inhibitor, clade C (antithrombin), member 1 Antithrombin monomer drawn from PDB 2ANT … Wikipedia
cell — cell1 cell like, adj. /sel/, n. 1. a small room, as in a convent or prison. 2. any of various small compartments or bounded areas forming part of a whole. 3. a small group acting as a unit within a larger organization: a local cell of the… … Universalium
Allosteric regulation — In biochemistry, allosteric regulation is the regulation of an enzyme or other protein by binding an effector molecule at the protein s allosteric site (that is, a site other than the protein s active site). Effectors that enhance the protein s… … Wikipedia
Enzyme — Biocatalyst redirects here. For the use of natural catalysts in organic chemistry, see Biocatalysis. Human glyoxalase I. Two zinc ions that are needed for the enzyme to catalyze its reaction are shown as purp … Wikipedia
Cholesterol-dependent cytolysin — Cholesterol Dependent Cytolysins (CDC) are a family of β barrel pore forming exotoxins that are secreted by Gram positive bacteria. CDC are secreted as water soluble monomers of 50 70 kDa, that once bound to the target cell, will form a circular… … Wikipedia
Macromolecular docking — is the computational modelling of the molecular structure of complexes formed by two or more interacting biological macromolecules. Protein protein complexes are the most commonly attempted targets, followed increasingly by protein nucleic acid… … Wikipedia
Kaliotoxin — (KTX) is an ion channel toxin which inhibits potassium flux through the Kv1.3 voltage gated potassium channel and calcium activated potassium channels by physically blocking the channel entrance and secondly KTX induces a conformational change in … Wikipedia
AMP-activated protein kinase — 5 AMP activated protein kinase or AMPK consists of three proteins (subunits) that together make a functional enzyme, conserved from yeast to humans, that plays a role in cellular energy homeostasis. It is expressed in a number of tissues,… … Wikipedia